Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
SERPINE1 MUTATION
SERPINE1 MUTATION
Associated Disease
Chronic Obstructive Airway Disease
Source Database
DisGeNET
Description
We found increased p53, PAI-1 and apoptosis in AECs, with accumulation of macrophages and neutrophils in the lungs of patients with COPD.
Pubmed
25932922
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD,RGD
DisGENET score for the Gene Disease association
0.0897395697864884
Drugs