Annotation Detail

Information
Associated Genes
ABCA1
Associated Variants
ABCA1 MUTATION
ABCA1 MUTATION
Associated Disease
Liver neoplasms
Source Database
DisGeNET
Description
We show that the up-regulation of ABCA1 gene expression and its cholesterol efflux function in Huh7.5 hepatoma cells, using the liver X receptor (LXR) agonist GW3965, impairs HCV infection and decreases levels of virus produced.
Pubmed
24646941
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs