Annotation Detail

Information
Associated Genes
SCN5A
Associated Variants
SCN5A p.Arg1623Leu (p.R1623L) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
SCN5A p.Arg1623Gln (p.R1623Q) ( ENST00000423572.7, ENST00000413689.6, ENST00000333535.9, ENST00000414099.6, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
SCN5A p.Arg1623Leu (p.R1623L) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
SCN5A p.Arg1623Gln (p.R1623Q) ( ENST00000333535.9, ENST00000413689.6, ENST00000414099.6, ENST00000423572.7, ENST00000449557.6, ENST00000450102.6, ENST00000455624.6 )
Associated Disease
long QT syndrome
Source Database
DisGeNET
Description
The surviving infant was found to have a heterozygous mutation in SCN5A (R1623Q), previously reported as a de novo mutation causing neonatal ventricular arrhythmia and LQTS.
Pubmed
15184283
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.334978501186199
Year of publication
2004
Drugs