Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
SERPINE1 MUTATION
SERPINE1 MUTATION
Associated Disease
liver cirrhosis
Source Database
DisGeNET
Description
In conclusion, thrombo and fibro-genetic mechanisms of PAI-1 4G-4G and MTHFR 677TT, could have a role in the development of liver cirrhosis, mainly in patients without HCV and HBV, and PVT.
Pubmed
25987440
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0103683299224339
Drugs