Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
-
ABCB1 MUTATION
ABCB1 MUTATION - Associated Disease
- liposarcoma
- Source Database
- DisGeNET
- Description
- These results show that bortezomib exhibits preferential cytotoxicity toward SW872-S cells possibly via highly expressed SERCA2-associated MDR1 suppression and suggest that bortezomib may serve as a potent agent for treating advanced liposarcoma.
- Pubmed
- 25576094
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs