Annotation Detail
Information
- Associated Genes
- RXRA
- Associated Variants
-
RXRA MUTATION
RXRA MUTATION - Associated Disease
- acute promyelocytic leukemia
- Source Database
- DisGeNET
- Description
- Here, we showed that homodimeric NUP98-RARG not only acquired unique nuclear localization pattern and ability of recruiting both RXRA and wild-type NUP98, but also exhibited similar transcriptional properties as RARA fusions found in acute promyelocytic leukemia (APL).
- Pubmed
- 25510432
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs