Annotation Detail
Information
- Associated Genes
- TP53
- Associated Variants
-
TP53 MUTATION
TP53 MUTATION - Associated Disease
- Leukemia, Myelocytic, Acute
- Source Database
- DisGeNET
- Description
- Consistent with these data, expression of JAK2V617F combined with Tp53 loss led to fully penetrant AML in vivo.
- Pubmed
- 25516983
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,CTD_mouse,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.156878977060362
Drugs