Annotation Detail
Information
- Associated Genes
- BPI
- Associated Variants
-
BPI p.Ala12Val (p.A12V)
(
ENST00000262865.9,
ENST00000642449.2 )
TNF c.-488G>A
BPI p.Ala12Val (p.A12V) ( ENST00000262865.9, ENST00000642449.2 )
TNF c.-488G>A - Associated Disease
- Septicaemia due to gram-negative organism, unspecified
- Source Database
- DisGeNET
- Description
- Genotype AG of rs1800629 (the LTA gene) and genotypes CC and CT of rs1341023 (the BPI gene) were associated with a significantly increased risk of developing Gram-negative sepsis (p = 0.04, p = 0.04 and p = 0.03).
- Pubmed
- 25000179
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2014
Drugs