Annotation Detail
Information
- Associated Genes
- MTHFR
- Associated Variants
-
ABCB1 p.Ile1145= (p.I1145=)
(
ENST00000265724.8,
ENST00000543898.5,
ENST00000622132.5 )
ABCB1 p.Ile1145= (p.I1145=) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 p.Ile1145= (p.I1145=) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 )
ABCB1 p.Ile1145= (p.I1145=) ( ENST00000265724.8, ENST00000543898.5, ENST00000622132.5 ) - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- These data suggest that the presence of the MTHFR C677T and ABCB1 C3435T SNPs contribute to MTX toxicity in patients with RA.
- Pubmed
- 23095111
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.204307729914934
- Year of publication
- 2012
Drugs