Annotation Detail

Information
Associated Genes
KMT2A
Associated Variants
KMT2A MUTATION
KMT2A MUTATION
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
Our recent study identified a nonsense mutation of La-related protein 4B (LARP4B) from whole genome sequencing of a 3-year-old female monozygotic twin pair discordant for MLL-associated acute myeloid leukemia (AML).
Pubmed
25534202
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,MGD
DisGENET score for the Gene Disease association
0.329618745023685
Drugs