Annotation Detail

Information
Associated Genes
KMT2A
Associated Variants
KMT2A MUTATION
KMT2A MUTATION
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
Here, we report that deletion of the Hes1 gene in mice promotes acute myeloid leukemia (AML) development induced by the MLL-AF9 fusion protein.
Pubmed
25234168
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,MGD
DisGENET score for the Gene Disease association
0.329618745023685
Drugs