Annotation Detail

Information
Associated Genes
TIRAP
Associated Variants
TIRAP MUTATION
TIRAP MUTATION
Associated Disease
Acute Megakaryocytic Leukemias
Source Database
DisGeNET
Description
Megakaryoblastic leukemia 1 (MKL1), also known as MAL or myocardin-related transcription factor A (MRTF-A), is a coactivator of serum response factor, which regulates transcription of actin and actin cytoskeleton-related genes.
Pubmed
26224645
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs