Annotation Detail

Information
Associated Genes
SOCS2
Associated Variants
SOCS2 MUTATION
SOCS2 MUTATION
Associated Disease
Acute lymphocytic leukemia
Source Database
DisGeNET
Description
High levels of SOCS2 characterize unfavorable subsets of acute myeloid and lymphoblastic leukemias, such as those with MLL and BCR/ABL abnormalities, and correlate with the enrichment of genes belonging to hematopoietic and leukemic stemness signatures.
Pubmed
25858143
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs