Annotation Detail

Information
Associated Genes
PIK3CB
Associated Variants
PIK3CB MUTATION
PIK3CB MUTATION
Associated Disease
chronic lymphocytic leukemia
Source Database
DisGeNET
Description
Altogether, these results underline the key role of PI3K/AKT pathway in the generation of the CLL proliferative pool and provide additional rationale for the usage of PI3K inhibitors.
Pubmed
24825182
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00325730246496364
Drugs