Annotation Detail
Information
- Associated Genes
- HTR1B
- Associated Variants
-
HTR1B MUTATION
HTR1B MUTATION
HTR1B p.Phe124Cys (p.F124C) ( ENST00000369947.5 )
HTR1B p.Phe124Ser (p.F124S) ( ENST00000369947.5 )
rs130058
HTR1B p.Phe124Cys (p.F124C) ( ENST00000369947.5 )
HTR1B p.Phe124Ser (p.F124S) ( ENST00000369947.5 )
rs130058 - Associated Disease
- Headache
- Source Database
- DisGeNET
- Description
- Genomic DNA of a relatively small but very well-characterized set of migraine patients with consistently good response to sumatriptan (n = 14), with no response (n = 12), with recurrence of the headache (n = 12), with chest symptoms (n = 13), and patients without chest symptoms (n = 27) was available for the genetic analyses and screened for the F124C variant and the A-161T polymorphism in the human 5-HT(1B) receptor gene.
- Pubmed
- 17501853
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2007
Drugs