Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
Associated Disease
Kidney Failure, Acute
Source Database
DisGeNET
Description
Targeting the HMGB1-TLR4 pathway might enable development of a new therapeutic strategy to improve the outcomes of severely ill patients with both acute lung and acute kidney injury.
Pubmed
24646859
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs