Annotation Detail

Information
Associated Genes
IFNL3
Associated Variants
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
Hepatitis B, Chronic
Source Database
DisGeNET
Description
To evaluate the role of host IL28B (interleukin 28B; interferon lambda 3) single nucleotide polymorphisms (SNPs) in predicting hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) susceptibility, three SNPs in the IL28B gene (rs12979860C/T, rs8099917G/T and rs12980275G/A) were examined in 330 subjects (including 154 HBV-related HCC patients, 86 non-HCC patients with chronic hepatitis B (CHB), 43 HBV self-limited infections and 47 healthy controls).
Pubmed
22310928
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00488595369744546
Year of publication
2012
Drugs