Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA MUTATION
VEGFA MUTATION
Associated Disease
Keloid
Source Database
DisGeNET
Description
Upregulated periostin promotes angiogenesis in keloids through activation of the ERK 1/2 and focal adhesion kinase pathways, as well as the upregulated expression of VEGF and angiopoietin‑1.
Pubmed
25369801
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs