Annotation Detail
Information
- Associated Genes
- MYCN
- Associated Variants
-
CASP8 p.Asp344His (p.D344H)
(
ENST00000264275.9,
ENST00000323492.11,
ENST00000358485.8,
ENST00000392263.6,
ENST00000413726.6,
ENST00000432109.6,
ENST00000440732.6,
ENST00000444430.3,
ENST00000450491.6,
ENST00000673742.1,
ENST00000696067.1,
ENST00000696069.1,
ENST00000696085.1,
ENST00000696087.1 )
CASP8 p.Asp344His (p.D344H) ( ENST00000264275.9, ENST00000323492.11, ENST00000358485.8, ENST00000392263.6, ENST00000413726.6, ENST00000432109.6, ENST00000440732.6, ENST00000444430.3, ENST00000450491.6, ENST00000673742.1, ENST00000696067.1, ENST00000696069.1, ENST00000696085.1, ENST00000696087.1 ) - Associated Disease
- neuroblastoma
- Source Database
- DisGeNET
- Description
- A missense SNP in exon 10 of the CASP8 gene SNP D302H was associated with worse overall and event-free survival in patients with MYCN-amplified neuroblastoma tumors.
- Pubmed
- 25502557
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.333621751212336
- Year of publication
- 2014
Drugs