Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
irritable bowel syndrome
Source Database
DisGeNET
Description
Additionally, polymorphisms of TNF-α gene are known to affect the gene expression level and particular TNF-α genotypes may influence the response of IBD patients treated with TNF-α inhibitors.
Pubmed
25386052
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0116396628910506
Drugs