Annotation Detail
Information
- Associated Genes
- TLR3
- Associated Variants
-
TLR3 MUTATION
TLR3 MUTATION - Associated Disease
- influenza
- Source Database
- DisGeNET
- Description
- These data show that H1N1 and poly(I:C) can induce αvβ6 integrin-dependent TGFβ activity in epithelial cells via stimulation of TLR3 and suggest a novel mechanism by which influenza infection may promote collagen deposition in fibrotic lung disease.
- Pubmed
- 25339175
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs