Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
TNF MUTATION
TNF MUTATION - Associated Disease
- Inflammatory Bowel Diseases
- Source Database
- DisGeNET
- Description
- SIRT1 expression was downregulated in control LPMC by tumor necrosis factor (TNF)-α and interleukin (IL)-21, and upregulated in IBD LPMC by neutralizing TNF-α and IL-21antibodies.
- Pubmed
- 24850427
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.182983240932536
Drugs