Annotation Detail

Information
Associated Genes
CFB
Associated Variants
ENSG00000244255 c.3362-61A>G, CFB c.1856-61A>G ( ENST00000425368.7, ENST00000483004.2, ENST00000698628.1 )
ENSG00000244255 c.3362-61A>G, CFB c.1856-61A>G ( ENST00000425368.7, ENST00000483004.2, ENST00000698628.1 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
[We identified and then confirmed through replication two new genetic loci for SLE: a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region.]
Pubmed
18204098
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.134202191871612
Year of publication
2008
Drugs