Annotation Detail
Information
- Associated Genes
- AKR1A1
- Associated Variants
-
ADH1B p.His48Arg (p.H48R)
(
ENST00000305046.13,
ENST00000506651.5,
ENST00000625860.2 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 ) - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- Genetic polymorphisms, aldehyde dehydrogenase (ALDH2) Glu487Lys and alcohol dehydrogenase 2 (ADH2) His47Arg, which have a strong impact on alcohol metabolism, are common in Japanese population but their significance for CRC carcinogenesis remains to be clarified in detail.
- Pubmed
- 16332725
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00217153497664243
- Year of publication
- 2006
Drugs