Annotation Detail

Information
Associated Genes
STAT5B
Associated Variants
STAT5B MUTATION
STAT5B MUTATION
Associated Disease
Hypergammaglobulinemia
Source Database
DisGeNET
Description
In conclusion, STAT-5 is activated constitutively in PB leucocytes in patients with pSS, and basal STAT-5 phosphorylation seems to associate with hypergammaglobulinaemia, anti-SSB antibody production and purpura.
Pubmed
25736842
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs