Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R c.653-2380G>A ( ENST00000697165.1, ENST00000347310.10, ENST00000697154.1, ENST00000371007.6, ENST00000697163.1, ENST00000697164.1, ENST00000697230.1 )
IL23R c.956-8194A>G ( ENST00000697163.1, ENST00000697230.1, ENST00000697164.1, ENST00000697165.1, ENST00000371007.6, ENST00000697154.1, ENST00000425614.3, ENST00000347310.10 )
ATG16L1 p.Thr317Ala (p.T317A) ( ENST00000347464.9, ENST00000373525.9, ENST00000392017.9, ENST00000392018.1, ENST00000392020.8 )
IL23R c.653-2380G>A ( ENST00000347310.10, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1, ENST00000371007.6 )
IL23R c.956-8194A>G ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1, ENST00000371007.6 )
ATG16L1 p.Thr317Ala (p.T317A) ( ENST00000347464.9, ENST00000373525.9, ENST00000392017.9, ENST00000392018.1, ENST00000392020.8 )
Associated Disease
Crohn Disease
Source Database
DisGeNET
Description
To investigate the interaction of interleukin-23 receptor (IL23R) (rs1004819 and rs2201841), autophagy-related 16-like 1 (ATG16L1) (rs2241880), caspase recruitment domain-containing protein 15 (CARD15) genes, and IBD5 locus in Crohn's disease (CD) patients.
Pubmed
20066736
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.370597434945242
Year of publication
2010
Drugs