Annotation Detail
Information
- Associated Genes
- LGR6
- Associated Variants
-
LGR6 MUTATION
LGR6 MUTATION - Associated Disease
- Huntington disease
- Source Database
- DisGeNET
- Description
- In addition, we show that the activation of autophagy by pharmacological inhibition of GPCR reduces the accumulation of misfolded proteins and protects against behavior dysfunction in a mouse model of Huntington's disease.
- Pubmed
- 25821988
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs