Annotation Detail
Information
- Associated Genes
- BDNF
- Associated Variants
-
BDNF MUTATION
BDNF MUTATION - Associated Disease
- Huntington disease
- Source Database
- DisGeNET
- Description
- Restoring neurotrophic support in HD remains a key potential therapeutic approach. with several approaches being pursued, including brain-derived neurotrophic factor (BDNF) mimesis through tyrosine receptor kinase B (TrkB) agonism and monoclonal antibodies.
- Pubmed
- 25155142
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0120828575467005
Drugs