Annotation Detail

Information
Associated Genes
VWF
Associated Variants
VWF p.Arg1205Leu (p.R1205L) ( ENST00000261405.10 )
VWF p.Arg1205His (p.R1205H) ( ENST00000261405.10 )
VWF p.Cys1130Phe (p.C1130F) ( ENST00000261405.10 )
VWF p.Arg1205Leu (p.R1205L) ( ENST00000261405.10 )
VWF p.Arg1205His (p.R1205H) ( ENST00000261405.10 )
VWF p.Cys1130Phe (p.C1130F) ( ENST00000261405.10 )
Associated Disease
von Willebrand Disease
Source Database
DisGeNET
Description
It was the aim of the present study to prospectively evaluate clinical events of 60 heterozygous patients with VWD Vicenza (VWD-VI) carrying R1205H VWF mutation and 23 with C1130F mutation, both characterised by markedly increased VWF clearance.
Pubmed
21264446
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.249618745023685
Year of publication
2011
Drugs