von Willebrand Disease

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Information
Disease name
von Willebrand Disease
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04953884 Active, not recruiting Phase 3 Efficacy, PK, Immunogenicity and Safety of Wilate in Severe Von Willebrand Disease VWD) Patients <6 Years of Age July 28, 2021 December 2024
NCT00555555 Active, not recruiting Phase 4 Efficacy of Alphanate FVIII/VWF Concentrate in Type 3 Von Willebrand Patients September 2007 March 2029
NCT00168090 Completed Phase 4 Study of Safety and Efficacy of Antihemophilic Factor/Von Willebrand Factor Complex in Surgical Subjects With Von Willebrand Disease (vWD) October 2001 May 2006
NCT01224808 Completed Phase 3 Extension Study of Biostate in Subjects With Von Willebrand Disease October 2010 March 2014
NCT00151125 Completed Phase 2 Phase II Study of IL-11 (Neumega) in Von Willebrand Disease July 2004 December 2007
NCT00994929 Completed Phase 2 Efficacy and Safety of IL-11 in DDAVP Unresponsive January 2010 April 2012
NCT01213446 Completed Phase 3 Study of Biostate® in Children With Von Willebrand Disease August 2010 August 2013
NCT00111215 Completed N/A Treatment and Management of Women With Bleeding Disorders January 2001 September 2006
NCT01410227 Completed Phase 3 Pharmacokinetics, Safety and Efficacy of Recombinant Von Willebrand Factor (rVWF) in the Treatment of Bleeding Episodes in Von Willebrand Disease (VWD) November 1, 2011 February 1, 2014
NCT01589848 Completed Study on Von Willebrand Disease and Hemophilia in Cuenca, Ecuador March 2013 June 2013
NCT01602419 Completed Surveillance of Safety and Efficacy of Wilate in Patients With Von Willebrand Disease October 2012 April 2018
NCT01949220 Completed Willebrand International Non-interventional Global Surveillance March 2014 December 2017
NCT02246881 Completed Phase 3 A Study to Compare the Pharmacokinetics and Safety of Current Factor VIII Concentrate and Optivate® in Haemophilia A. October 2001
NCT02283268 Completed Phase 3 Recombinant Von Willebrand Factor in Subjects With Severe Von Willebrand Disease Undergoing Surgery April 1, 2015 July 6, 2016
NCT02552576 Completed Phase 4 Study of Voncento® in Subjects With Von Willebrand Disease October 5, 2015 February 15, 2018
NCT02792205 Completed Performance Evaluation of Von Willebrand:Collagen-Binding Assays to Diagnose Von Willebrand Factor Deficiency in Patients With Increased Risk of Bleeding February 22, 2017 June 30, 2021
NCT02973087 Completed Phase 3 rVWF IN PROPHYLAXIS November 16, 2017 July 6, 2020
NCT04657887 Completed Registry of Patients With Von WilLEbrand Disease Treated With Voncento® November 23, 2015 December 31, 2023
NCT00510042 Completed National Study of Moderate and Severe Von Willebrand Disease in the Netherlands July 2007 September 2009
NCT00524342 Completed Phase 2 IL-11 in Women With Von Willebrand Disease and Refractory Menorrhagia January 2008 December 2010
NCT00557908 Completed The Von Willebrand Disease (VWD) International Prophylaxis Study June 2007 February 2013
NCT00701545 Completed A Canadian Study to Assess the Safety of Humate-P® Ivr (Infusion Volume Reduced) February 2008 April 2009
NCT00805051 Completed Acquired Von Willebrand Syndrome in Severe Aortic Stenosis October 2008 August 2010
NCT00816660 Completed Phase 1 Pharmacokinetic, Safety and Tolerability Study of Recombinant Von Willebrand Factor / Recombinant Factor VIII Complex in Type 3 Von Willebrand Disease December 1, 2008 August 31, 2010
NCT00941616 Completed Phase 2/Phase 3 Study of a pd VWF/FVIII Concentrate, Biostate®, in Subjects With Von Willebrand Disease June 2009 February 2012
NCT02472665 Recruiting Phase 4 Efficacy and Safety of Fanhdi®, a High-purity Von Willebrand Containing FVIII Concentrate, in Pediatric Patients With Von Willebrand Disease December 2013 December 2024
NCT02932618 Recruiting Phase 3 A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD) December 18, 2017 January 1, 2025
NCT00404300 Terminated Phase 3 Optivate in People With Von Willebrand Disease Undergoing Surgery February 2007 September 2008
NCT00524225 Terminated Phase 2 IL-11 in Adults With Von Willebrand Disease Undergoing Surgery February 2008 June 2012
NCT00178542 Terminated Change in Thrombin Generation Potential and Thromboelastography During the Menstrual Cycle September 2005 April 2013
NCT00387192 Terminated Phase 3 A Study With OPTIVATE® in People With Von Willebrand Disease November 2006 September 2008
NCT02869074 Unknown status Molecular and Clinical Profile of Von Willebrand Disease in Spain October 3, 2017 August 31, 2021
NCT01261936 Unknown status Evaluation of Menses in Congenital Bleeding Disorders February 2010 December 2011
NCT03521583 Unknown status Von Willebrand Disease in the Netherlands July 28, 2019 January 2022
NCT04279717 Unknown status Latin-American Von Willebrand Disease Registry February 2020 December 2022
NCT00630448 Withdrawn Collection of Blood in Normal Subjects and Subjects With Von Willebrand Disease (VWD) November 2008 July 2011
NCT00694785 Withdrawn Phase 2 A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of ARC1779 Injection in Patients With Von Willebrand Disease Type 2B October 2008
NCT01651468 Withdrawn N/A The Effect of the Nutraceutical "Hemofix" on the Coagulation System September 2016 December 2023
OrphaNumber from OrphaNet (Orphanet)
903
ICD10 preferred id (Insert disease from ICD10)
D0003246
ICD10 class code (Insert disease from ICD10)
D68.0