Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
TLR2 MUTATION
TLR2 MUTATION
Associated Disease
Herpes Simplex Infections
Source Database
DisGeNET
Description
The PAMP of the HSV-induced innate response is the gH/gL virion glycoprotein, which interacts with αvβ3-integrin and TLR2 independently one of the other, and cross-links the two receptors.
Pubmed
25375272
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs