Annotation Detail
Information
- Associated Genes
- TNFSF10
- Associated Variants
-
TNFSF10 MUTATION
TNFSF10 MUTATION - Associated Disease
- hepatitis C
- Source Database
- DisGeNET
- Description
- We demonstrated a marked polarization of NK cells toward cytotoxicity in response to IFN-α stimulation in patients with hepatitis C. That TRAIL up-regulation was present, particularly in patients with the IFNL3-TT allele, was supported by a shift in the pSTAT-1:pSTAT-4 ratios toward pSTAT-1.
- Pubmed
- 26034208
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00381011773078838
Drugs