Annotation Detail
Information
- Associated Genes
- ERCC4
- Associated Variants
-
PGR p.Val660Leu (p.V660L)
(
ENST00000534013.5,
ENST00000263463.9,
ENST00000619228.2,
ENST00000325455.10 )
ERCC4 c.208-807G>C ( ENST00000311895.8, ENST00000575156.5, ENST00000682617.1 )
BID p.Ser56Gly (p.S56G) ( ENST00000317361.11, ENST00000342111.9, ENST00000399765.5, ENST00000399767.6, ENST00000551952.5, ENST00000614949.4, ENST00000622694.5 )
CASP10 p.Val410Ile (p.V410I) ( ENST00000272879.9, ENST00000286186.11, ENST00000313728.12, ENST00000346817.10, ENST00000448480.1, ENST00000696199.1 )
NC_000006.12:g.31575324G>A
PGR p.Val660Leu (p.V660L) ( ENST00000263463.9, ENST00000325455.10, ENST00000534013.5, ENST00000619228.2 )
ERCC4 c.208-807G>C ( ENST00000311895.8, ENST00000575156.5, ENST00000682617.1 )
BID p.Ser56Gly (p.S56G) ( ENST00000317361.11, ENST00000342111.9, ENST00000399765.5, ENST00000399767.6, ENST00000551952.5, ENST00000614949.4, ENST00000622694.5 )
CASP10 p.Val410Ile (p.V410I) ( ENST00000272879.9, ENST00000286186.11, ENST00000313728.12, ENST00000346817.10, ENST00000448480.1, ENST00000696199.1 )
NC_000006.12:g.31575324G>A - Associated Disease
- Invasive breast carcinoma
- Source Database
- DisGeNET
- Description
- In conclusion, our data provide persuasive evidence against an overall association between invasive breast cancer risk and ERCC4 rs744154, TNF rs361525, CASP10 rs13010627, PGR rs1042838, and BID rs8190315 genotypes among women of European descent.
- Pubmed
- 19423537
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs