Annotation Detail
Information
- Associated Genes
- IL6
- Associated Variants
-
IL6 MUTATION
IL6 MUTATION - Associated Disease
- Graves Disease
- Source Database
- DisGeNET
- Description
- Increased level of IL-37 in patients with GD are associated with TNF-α, IL-6, IL-17 and disease activity, and it plays a protective role against inflammatory effect in GD by inhibiting the production of proinflammatory cytokines.
- Pubmed
- 25226272
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00717704080592679
Drugs