Annotation Detail

Information
Associated Genes
CD34
Associated Variants
CD34 MUTATION
CD34 MUTATION
Associated Disease
chronic granulomatous disease
Source Database
DisGeNET
Description
Using a standard platform that combines iPSC generation from peripheral blood CD34(+) cells and ZFN mediated AAVS1 safe harbor minigene targeting, we demonstrate efficient generation of genetically corrected iPSCs using an identical approach for all five genetic forms of CGD.
Pubmed
25288370
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs