Annotation Detail

Information
Associated Genes
IDH1
Associated Variants
IDH1 p.Arg132His (p.R132H) ( ENST00000345146.7, ENST00000415913.5, ENST00000446179.5 )
IDH1 p.Arg132His (p.R132H) ( ENST00000345146.7, ENST00000415913.5, ENST00000446179.5 )
Associated Disease
anaplastic astrocytoma
Source Database
DisGeNET
Description
The IDH1 c.G395A; p.R132H mutation was observed in 56 and 94 % of grade II and grade III astrocytoma cases, respectively.
Pubmed
23934769
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00678604680200758
Year of publication
2014
Drugs