Annotation Detail

Information
Associated Genes
CASP8
Associated Variants
CASP8 MUTATION
CASP8 MUTATION
Associated Disease
IgA glomerulonephritis
Source Database
DisGeNET
Description
We investigated whether polymorphisms of apoptotic genes such as B-cell CLL/lymphoma 2 (BCL2), BH3-interacting domain death agonist (BID), and caspase 8 (CASP8) were associated with immunoglobulin A nephropathy (IgAN) and with the clinical phenotypes of IgAN patients.
Pubmed
24621205
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs