Annotation Detail

Information
Associated Genes
CYP19A1
Associated Variants
CYP19A1 MUTATION
CYP19A1 MUTATION
Associated Disease
Glioma
Source Database
DisGeNET
Description
All glioma cell lines included here expressed CYP19A1 and letrozole exerted considerable cytotoxicity and decrease in aromatase activity against these cells (IC50, 0.1-3.5 μmol/L).
Pubmed
25695958
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs