Annotation Detail
Information
- Associated Genes
- PIK3CD
- Associated Variants
-
PIK3CD MUTATION
PIK3CD MUTATION - Associated Disease
- Glioma
- Source Database
- DisGeNET
- Description
- The loss of MAGI3 expression in glioma may enhance the proliferation of glioma cells via downregulation of PTEN expression, leading to the activation of the PI3K/Akt pathway.MAGI3 is a potential glioma suppressor.
- Pubmed
- 26248734
- Section of the abstract supporting the evidence
- CONCLUSION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00922902365073031
Drugs