Annotation Detail

Information
Associated Genes
PDGFRA
Associated Variants
PDGFRA MUTATION
PDGFRA MUTATION
Associated Disease
Glioma
Source Database
DisGeNET
Description
We specifically demonstrate that loss of CTCF at a domain boundary permits a constitutive enhancer to interact aberrantly with the receptor tyrosine kinase gene PDGFRA, a prominent glioma oncogene.
Pubmed
26700815
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.011420421670701
Drugs