Annotation Detail
Information
- Associated Genes
- NRAS
- Associated Variants
-
NRAS p.Gly12Val (p.G12V)
(
ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 )
NRAS p.Gly12Val (p.G12V) ( ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 ) - Associated Disease
- leukemia
- Source Database
- DisGeNET
- Description
- Injecting Mx1-Cre, LSL-Nras(G12D) mice with the MOL4070LTR retrovirus causes acute myeloid leukemia that faithfully recapitulates many aspects of human NRAS-associated leukemias, including cooperation with deregulated Evi1 expression.
- Pubmed
- 21163920
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00488595369744546
- Year of publication
- 2011
Drugs