Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS p.Gly12Val (p.G12V) ( ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 )
NRAS p.Gly12Val (p.G12V) ( ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 )
Associated Disease
Leukemia, Myelocytic, Acute
Source Database
DisGeNET
Description
To elucidate the downstream functions of activated NRAS in AML, we used a murine model that harbors Mll-AF9 and a tetracycline-repressible, activated NRAS (NRAS(G12V)).
Pubmed
25316678
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0386518234021678
Year of publication
2015
Drugs