Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS p.Gly12Val (p.G12V) ( ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 )
NRAS p.Gly12Val (p.G12V) ( ENST00000369535.5 )
NRAS p.Gly12Ala (p.G12A) ( ENST00000369535.5 )
NRAS p.Gly12Asp (p.G12D) ( ENST00000369535.5 )
Associated Disease
melanoma
Source Database
DisGeNET
Description
In a limited validation of potentially actionable low frequency mutations, a NRAS G12D mutation in a melanoma was shown to be a false positive.
Pubmed
24885028
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.235804411506151
Year of publication
2014
Drugs