Annotation Detail
Information
- Associated Genes
- PIK3CG
- Associated Variants
-
PIK3CG MUTATION
PIK3CG MUTATION - Associated Disease
- Glioma
- Source Database
- DisGeNET
- Description
- The loss of MAGI3 expression in glioma may enhance the proliferation of glioma cells via downregulation of PTEN expression, leading to the activation of the PI3K/Akt pathway.MAGI3 is a potential glioma suppressor.
- Pubmed
- 26248734
- Section of the abstract supporting the evidence
- CONCLUSION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.0146777241356647
Drugs