Annotation Detail
Information
- Associated Genes
- OLIG2
- Associated Variants
-
OLIG2 MUTATION
OLIG2 MUTATION - Associated Disease
- glioblastoma
- Source Database
- DisGeNET
- Description
- Induction of the miR-302/367 cluster in extensively mutated U87MG glioblastoma cells drastically suppressed the expression of transformation related proteins, for example, the reprogramming factors OCT3/4, SOX2, KLF4 and c-MYC, and the transcription factors POU3F2, SALL2 and OLIG2, required for the maintenance of glioblastoma stem-like tumor propagating cells.
- Pubmed
- 25991553
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00924888669405859
Drugs