Annotation Detail

Information
Associated Genes
ABCB1
Associated Variants
ABCB1 MUTATION
ABCB1 MUTATION
Associated Disease
glioblastoma
Source Database
DisGeNET
Description
Taken together, we confirmed P-gp targeting of TMZ, a crucial regulator of TMZ resistance in GBM.
Pubmed
26208431
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0124302442889015
Drugs