Annotation Detail

Information
Associated Genes
GAA
Associated Variants
GAA MUTATION
GAA MUTATION
Associated Disease
Friedreich ataxia
Source Database
DisGeNET
Description
Molecular testing for Friedreich ataxia showed significantly expanded GAA repeats at 799 (abnormal >67 GAA repeats) on one allele and a heterozygous disease causing mutation, c.317T>C (p.Leu106Ser) on the other allele, confirming the diagnosis.
Pubmed
25149925
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0225296753826652
Drugs