Annotation Detail

Information
Associated Genes
GAA
Associated Variants
GAA MUTATION
GAA MUTATION
Associated Disease
Friedreich ataxia
Source Database
DisGeNET
Description
To determine the potential role of the other component of the MutLα complex, MLH1, in GAA repeat instability in FRDA, we have analyzed intergenerational and somatic GAA repeat expansions from FXN transgenic mice that have been crossed with Mlh1 deficient mice.
Pubmed
24971578
Section of the abstract supporting the evidence
METHODOLOGY/PRINCIPAL FINDINGS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0225296753826652
Drugs