Annotation Detail

Information
Associated Genes
KCNH2
Associated Variants
KCNH2 p.Thr65Pro (p.T65P) ( ENST00000262186.10, ENST00000713710.1 )
KCNH2 p.Thr65Pro (p.T65P) ( ENST00000262186.10, ENST00000713710.1 )
Associated Disease
long QT syndrome
Source Database
DisGeNET
Description
A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.
Pubmed
12354768
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.38848280393755
Year of publication
2002
Drugs