Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R MUTATION
IL23R MUTATION
Associated Disease
Experimental Autoimmune Encephalomyelitis
Source Database
DisGeNET
Description
In vivo IL-7/anti-IL-7 mAb complexes selectively expanded and enhanced the proliferation of CXCR3-expressing Th1 cells, but did not impact Th17 cells and EAE development in wild-type and IL-23R-deficient mice.
Pubmed
26223651
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs